Born in Italy and raised in Argentina, Giorgio di Sant’Angelo immigrated to the United States in 1962. After working as a textile and jewelry designer in New York for several years, he founded his label, Sant’Angelo, in 1966, as well as Sant’Angelo Ready-to-Wear that same year. Sant’Angelo’s early designs evoked ethnic and hippie clothing styles, but he transitioned to body-conscious knits and wovens after 1972. Throughout his career, Sant’Angelo’s designs were distinguished by their bright colors and vibrant patterns. Among other accolades, Sant'Angelo received the Coty American Fashion Critics Award in 1968 and 1970, the Council of Fashion Designers of America Award in 1987, and the Fashion Designers of America Award in 1988.